CCL2 Antibody - middle region

Artikelnummer: ASB-AVARP07046_P050
Artikelname: CCL2 Antibody - middle region
Artikelnummer: ASB-AVARP07046_P050
Hersteller Artikelnummer: AVARP07046_P050
Alternativnummer: ASB-AVARP07046_P050-25UL,ASB-AVARP07046_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Canine, Human
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCL2
Alternative Synonym: HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30
CCL2 is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. CCL2 augments monocyte anti-tumor activity. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. CCL2 may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 11kDa
NCBI: 6347
UniProt: P13500
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: Kidney
Sample Type:AHuman Macrophange Cells
Green:Aprimary
Red:Aphallodin
Blue:ADAPI
Yellow:Agreen/red
Primary Dilution:A1:200
Secondary Antibody:Aanti-Rabbit IgG-FITC
Secondary Dilution:A1:1000
Image Submitted By:AMilan Fiala
University of California, Los AngelesA
WB Suggested Anti-CCL2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T
CCL2 antibody - middle region (AVARP07046_P050) in Human 293T using Western Blot