CAV2 Antibody - N-terminal region

Artikelnummer: ASB-AVARP09020_P050
Artikelname: CAV2 Antibody - N-terminal region
Artikelnummer: ASB-AVARP09020_P050
Hersteller Artikelnummer: AVARP09020_P050
Alternativnummer: ASB-AVARP09020_P050-25UL,ASB-AVARP09020_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAV2
Alternative Synonym: CAV
CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 18kDa
NCBI: 858
UniProt: P51636
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type:
Human placental tissue Primary Antibody Dilution:
1:50Secondary Antibody:
Goat anti rabbit-HRP Secondary Antibody Dilution:
1:10,000Color/Signal Descriptions:
Brown: CAV2Purple: HaemotoxylinGene Name:
CAV2Submitted by:
Dr. Hiten D. Mistry and Anna Czajka, Kings College London, Lesia Kurlak, University of Nottingham
WB Suggested Anti-CAV2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Lung
Lanes:
Lane1: 50 ug human placental tissue lysate
Lane2: 40 ug human placental tissue lysate
Lane3: 30 ug human placental tissue lysate
Lane4: 20 ug human placental tissue lysate
Lane5: 20 ug human myometrial tissue lysate
Primary Antibody Dilution:
1:500
Secondary Antibody:
Goat anti-rabbit HRP
Secondary Antibody Dilution:
1:10000
Gene Name:
Caveolin 2
Submitted by:
Hiten Mistry, Ania Czajka and Marta Hentschke Ribeiro, Kings College London
CAV2 antibody - N-terminal region (AVARP09020_P050) in Human Lung using Western Blot