The immunogen is a synthetic peptide directed towards the N terminal region of human CAV3
Alternative Synonym:
LQT9, MPDT, RMD2, VIP21, LGMD1C, VIP-21
CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: Human placental tissue Primary Antibody Dilution: 1:50Secondary Antibody: Goat anti rabbit-HRP Secondary Antibody Dilution: 1:10,000Color/Signal Descriptions: Brown: CAV3Purple: HaemotoxylinGene Name: CAV3Submitted by: Dr. Hiten D. Mistry and Anna Czajka, Kings College London, Lesia Kurlak, University of Nottingham
Lanes: Lane1: 50 ug human placental tissue lysate Lane2: 40 ug human placental tissue lysate Lane3: 30 ug human placental tissue lysate Lane4: 20 ug human placental tissue lysate Lane5: 20 ug human myometrial tissue lysate Primary Antibody Dilution: 1:500 Secondary Antibody: Goat anti-rabbit HRP Secondary Antibody Dilution: 1:10000 Gene Name: Caveolin 3 Submitted by: Hiten Mistry, Ania Czajka and Marta Hentschke Ribeiro, Kings College London
CAV3 antibody - N-terminal region (AVARP09021_P050) in Human Muscle using Western Blot
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