CAV3 Antibody - N-terminal region

Artikelnummer: ASB-AVARP09021_P050
Artikelname: CAV3 Antibody - N-terminal region
Artikelnummer: ASB-AVARP09021_P050
Hersteller Artikelnummer: AVARP09021_P050
Alternativnummer: ASB-AVARP09021_P050-25UL,ASB-AVARP09021_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Human, Mouse, Porcine, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAV3
Alternative Synonym: LQT9, MPDT, RMD2, VIP21, LGMD1C, VIP-21
CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 17kDa
NCBI: 859
UniProt: P56539
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type:
Human placental tissue Primary Antibody Dilution:
1:50Secondary Antibody:
Goat anti rabbit-HRP Secondary Antibody Dilution:
1:10,000Color/Signal Descriptions:
Brown: CAV3Purple: HaemotoxylinGene Name:
CAV3Submitted by:
Dr. Hiten D. Mistry and Anna Czajka, Kings College London, Lesia Kurlak, University of Nottingham
WB Suggested Anti-CAV3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human muscle
Lanes:
Lane1: 50 ug human placental tissue lysate
Lane2: 40 ug human placental tissue lysate
Lane3: 30 ug human placental tissue lysate
Lane4: 20 ug human placental tissue lysate
Lane5: 20 ug human myometrial tissue lysate
Primary Antibody Dilution:
1:500
Secondary Antibody:
Goat anti-rabbit HRP
Secondary Antibody Dilution:
1:10000
Gene Name:
Caveolin 3
Submitted by:
Hiten Mistry, Ania Czajka and Marta Hentschke Ribeiro, Kings College London
CAV3 antibody - N-terminal region (AVARP09021_P050) in Human Muscle using Western Blot