PSMA1 (AAH02577, 1 a.a. ~ 263 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Synonym:
30 kDa prosomal protein,epididymis secretory protein Li 275,HC2,HEL-S-275,macropain subunit C2,macropain subunit nu,multicatalytic endopeptidase complex subunit C2,NU,PROS30,PROS-30,proteasome (prosome, macropain) subunit, alpha type, 1,proteasome component C2,proteasome nu chain,proteasome subunit alpha 1,proteasome subunit alpha 6,proteasome subunit alpha type-1,proteasome subunit nu,proteasome subunit, alpha-type, 1,protein P30-33K,testicular tissue protein Li 150.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms
