Recombinant Human Histone chaperone ASF1A protein (1-204AA)
Konjugation:
Unconjugated
Alternative Synonym:
anti-silencing function protein 1 homolog A,ASF1 anti-silencing function 1 homolog A,CCG1-interacting factor A,CGI-98,CIA,hAsf1,hAsf1a,hCIA,histone chaperone ASF1A,HSPC146.
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
