Recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein (25-292AA)
Konjugation:
Unconjugated
Alternative Synonym:
11-beta-HSD1,11-beta-hydroxysteroid dehydrogenase 1,11-DH,corticosteroid 11-beta-dehydrogenase isozyme 1,CORTRD2,HDL,HSD11,HSD11B,HSD11L,SDR26C1,short chain dehydrogenase/reductase family 26C member 1.
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).