MTM1 Antibody
Artikelnummer:
ASB-OACA06952
- Bilder (3)
| Artikelname: | MTM1 Antibody |
| Artikelnummer: | ASB-OACA06952 |
| Hersteller Artikelnummer: | OACA06952 |
| Alternativnummer: | ASB-OACA06952-100UL,ASB-OACA06952-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human Myotubularin protein (484-603AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | CNM,MTMX,myotubularin,phosphatidylinositol-3,5-bisphosphate 3-phosphatase,phosphatidylinositol-3-phosphate phosphatase,XLMTM. |
| Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis. |
| Klonalität: | Polyclonal |
| NCBI: | 4534 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human epityphlon at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human pancreas at dilution 1:100 |
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All lanes: Myotubularin antibody at 2ug/ml Lane 1: Jurkat whole cell lysate Lane 2: HepG2 wh |
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