Recombinant Human Intermediate conductance calcium-activated potassium channel protein 4 protein (288-427AA)
Konjugation:
Unconjugated
Alternative Synonym:
DHS2,hIKCa1,hKCa4,hSK4,IK,IK1,IKCA1,intermediate conductance calcium-activated potassium channel protein 4,intermediate-conductance Ca2+-activated K+ channel, KCa3.1,KCa3.1,KCA4,potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4,potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4,putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel,putative Gardos channel,SK4,SKCa 4,SKCa4,small conductance calcium-activated potassium channel 4.
Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614).
