Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1 protein (1-180AA)
Konjugation:
Unconjugated
Alternative Synonym:
C21,DC42,F-box-like/WD repeat-containing protein TBL1XR1,IRA1,MRD41,nuclear receptor co-repressor/HDAC3 complex subunit,nuclear receptor corepressor/HDAC3 complex subunit TBLR1,TBL1-related protein 1,TBLR1,transducin beta like 1 X-linked receptor 1,Transducin beta-like 1X-related protein 1.
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
