CD6 Antibody
Artikelnummer:
ASB-OACA07484
- Bilder (3)
| Artikelname: | CD6 Antibody |
| Artikelnummer: | ASB-OACA07484 |
| Hersteller Artikelnummer: | OACA07484 |
| Alternativnummer: | ASB-OACA07484-100UL,ASB-OACA07484-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human T-cell differentiation antigen CD6 protein (424-668AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | CD6 antigen,T12,T-cell differentiation antigen CD6,TP120. |
| Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24945728, PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule, promotes T-cell activation and proliferation (PubMed:15294938, PubMed:16352806, PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938, PubMed:16352806). Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria (PubMed:17601777). LPS binding leads to the activation of signaling cascades and down-stream MAP kinases (PubMed:17601777). Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS (PubMed:17601777). |
| Klonalität: | Polyclonal |
| NCBI: | 923 |
| Formulierung: | Liquid |
|
|
Immunohistochemistry of paraffin-embedded human thymus at dilution 1:100 |
|
|
Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100 |
|
|
All lanes: CD6 antibody at 4ug/ml Lane 1: Hela whole cell lysate Lane 2: jurkat whole cell |
Produktgarantie und fachkundiger Support
