Recombinant Human Melanoma-associated antigen 6 protein (75-314AA)
Konjugation:
Unconjugated
Alternative Synonym:
cancer/testis antigen 1.6,cancer/testis antigen family 1, member 6,CT1.6,MAGE-3b,MAGE3B,MAGE3B antigen,MAGE6,MAGE-6 antigen,melanoma antigen family A, 6,melanoma antigen family A6,melanoma-associated antigen 6.
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.