ROCK2 Antibody
Artikelnummer:
ASB-OACA07795
- Bilder (3)
| Artikelname: | ROCK2 Antibody |
| Artikelnummer: | ASB-OACA07795 |
| Hersteller Artikelnummer: | OACA07795 |
| Alternativnummer: | ASB-OACA07795-100UL,ASB-OACA07795-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IF, IHC, WB |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | Recombinant Human Rho-associated protein kinase 2 protein (1109-1388AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | p164 ROCK-2,Rho kinase 2,rho-associated protein kinase 2,Rho-associated, coiled-coil-containing protein kinase 2,rho-associated, coiled-coil-containing protein kinase II,ROCK-II. |
| Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation. |
| Klonalität: | Polyclonal |
| NCBI: | 9475 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100 |
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Western blot All lanes: ROCK2 antibody at 2ug/ml+rat brain tissue Secondary G |
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