PPM1D Antibody
Artikelnummer:
ASB-OACA07882
- Bilder (3)
| Artikelname: | PPM1D Antibody |
| Artikelnummer: | ASB-OACA07882 |
| Hersteller Artikelnummer: | OACA07882 |
| Alternativnummer: | ASB-OACA07882-100UL,ASB-OACA07882-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | Recombinant Human Protein phosphatase 1D protein (1-250AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | IDDGIP,JDVS,p53-induced protein phosphatase 1,PP2C-DELTA,protein phosphatase 1D,Protein phosphatase 2C isoform delta,Protein phosphatase magnesium-dependent 1 delta,protein phosphatase Wip1,wild-type p53-induced phosphatase 1,WIP1. |
| Involved in the negative regulation of p53 expression (PubMed:23242139). Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates Ser-15 of TP53 and Ser-345 of CHEK1 which contributes to the functional inactivation of these proteins (PubMed:15870257, PubMed:16311512). Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity). |
| Klonalität: | Polyclonal |
| NCBI: | 8493 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100 |
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Western blot All lanes: APPM1Dantibody at 2.66ug/ml Lane 1A: Rat gonadal tissue |
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