Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform protein (1-320AA)
Konjugation:
Unconjugated
Alternative Synonym:
B alpha regulatory subunit,B56G,B56gamma,PP2A B subunit isoform B56-gamma,PP2A B subunit isoform B-gamma,PP2A B subunit isoform PR61-gamma,PP2A B subunit isoform R5-gamma,PR61G,protein phosphatase 2 regulatory subunit B, gamma,renal carcinoma antigen NY-REN-29,serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform.
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.