PPP2R5C Antibody

Artikelnummer: ASB-OACA07883
Artikelname: PPP2R5C Antibody
Artikelnummer: ASB-OACA07883
Hersteller Artikelnummer: OACA07883
Alternativnummer: ASB-OACA07883-100UL,ASB-OACA07883-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform protein (1-320AA)
Konjugation: Unconjugated
Alternative Synonym: B alpha regulatory subunit,B56G,B56gamma,PP2A B subunit isoform B56-gamma,PP2A B subunit isoform B-gamma,PP2A B subunit isoform PR61-gamma,PP2A B subunit isoform R5-gamma,PR61G,protein phosphatase 2 regulatory subunit B, gamma,renal carcinoma antigen NY-REN-29,serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform.
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.
Klonalität: Polyclonal
NCBI: 5527
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Western blot
All lanes: PPP2R5C antibody at 1.31ug/ml
Lane 1: MM231 whole cell lysate<