EIF2S3 Antibody

Artikelnummer: ASB-OACA08017
Artikelname: EIF2S3 Antibody
Artikelnummer: ASB-OACA08017
Hersteller Artikelnummer: OACA08017
Alternativnummer: ASB-OACA08017-100UL,ASB-OACA08017-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 protein (173-472AA)
Konjugation: Unconjugated
Alternative Synonym: EIF2,EIF2G,eIF-2gA,EIF2gamma,eIF-2-gamma X,eIF-2gX,eukaryotic translation initiation factor 2 subunit 3,eukaryotic translation initiation factor 2 subunit gamma X,eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa,eukaryotic translation initiation factor 2G,MEHMO,MRXSBRK.
As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (By similarity). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity).
Klonalität: Polyclonal
NCBI: 1968
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100
Western blot
All lanes: EIF2S3antibody at 0.83ug/ml+ Hela whole cell lysate
Goat