ERO1A Antibody
Artikelnummer:
ASB-OACA08318
- Bilder (3)
| Artikelname: | ERO1A Antibody |
| Artikelnummer: | ASB-OACA08318 |
| Hersteller Artikelnummer: | OACA08318 |
| Alternativnummer: | ASB-OACA08318-100UL,ASB-OACA08318-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human ERO1-like protein alpha protein (24-260AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | endoplasmic oxidoreductin-1-like protein,endoplasmic reticulum oxidoreductase alpha,Ero1alpha,ERO1-alpha,ERO1L,ERO1-L,ERO1LA,ERO1-L-alpha,ERO1-like protein alpha,oxidoreductin-1-L-alpha. |
| Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1. |
| Klonalität: | Polyclonal |
| NCBI: | 30001 |
| Formulierung: | Liquid |
|
|
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100 |
|
|
Immunohistochemistry of paraffin-embedded human small intestine tissue at dilution 1:100 |
|
|
Western blot All lanes: ERO1L antibody at 1.25ug/ml Lane 1A: A431 whol |
Produktgarantie und fachkundiger Support
