ZBTB48 Antibody
Artikelnummer:
ASB-OACA08411
- Bilder (3)
| Artikelname: | ZBTB48 Antibody |
| Artikelnummer: | ASB-OACA08411 |
| Hersteller Artikelnummer: | OACA08411 |
| Alternativnummer: | ASB-OACA08411-100UL,ASB-OACA08411-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human, Mouse |
| Immunogen: | Recombinant Human Telomere zinc finger-associated protein (1-280AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | GLI-Kruppel family member HKR3,HKR3,krueppel-related zinc finger protein 3,pp9964,telomere zinc finger-associated protein,telomeric zinc finger-associated protein,TZAP,zinc finger and BTB domain-containing protein 48,zinc finger protein 855,ZNF855. |
| Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5-TTAGGG-3 repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891). |
| Klonalität: | Polyclonal |
| NCBI: | 3104 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human lung tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100 |
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Western blot All lanes: ZBTB48 antibody at 0.31ug/ml Lane 1A: 293T whole cell lysate< |
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