RAB23 Antibody
Artikelnummer:
ASB-OACA08475
- Bilder (3)
| Artikelname: | RAB23 Antibody |
| Artikelnummer: | ASB-OACA08475 |
| Hersteller Artikelnummer: | OACA08475 |
| Alternativnummer: | ASB-OACA08475-100UL,ASB-OACA08475-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Ras-related protein Rab-23 protein (1-237AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | HSPC137,RAB family small GTP binding protein RAB 23,ras-related protein Rab-23. |
| The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes. |
| Klonalität: | Polyclonal |
| NCBI: | 51715 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100 |
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Western blot All lanes: RAB23 antibody at 3.88ug/ml Lane 1: Mouse ocular tissu |
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