MLF1 Antibody

Artikelnummer: ASB-OACA08520
Artikelname: MLF1 Antibody
Artikelnummer: ASB-OACA08520
Hersteller Artikelnummer: OACA08520
Alternativnummer: ASB-OACA08520-100UL,ASB-OACA08520-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human, Mouse
Immunogen: Recombinant Human Myeloid leukemia factor 1 protein (1-268AA)
Konjugation: Unconjugated
Alternative Synonym: myelodysplasia-myeloid leukemia factor 1,myeloid leukemia factor 1,testis tissue sperm-binding protein Li 49e.
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Klonalität: Polyclonal
NCBI: 4291
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Western blot
All lanes: MLF1 antibody at 4.05ug/ml+ Mouse brain tissue
Goat polyclona