VRK1 Antibody

Artikelnummer: ASB-OACA08538
Artikelname: VRK1 Antibody
Artikelnummer: ASB-OACA08538
Hersteller Artikelnummer: OACA08538
Alternativnummer: ASB-OACA08538-100UL,ASB-OACA08538-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Serine/threonine-protein kinase VRK1 protein (257-396AA)
Konjugation: Unconjugated
Alternative Synonym: PCH1,PCH1A,serine/threonine-protein kinase VRK1,vaccinia related kinase 1,vaccinia virus B1R-related kinase 1,Vaccinia-related kinase 1.
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates Thr-18 of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.
Klonalität: Polyclonal
NCBI: 7443
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human lung tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Western blot
All lanes: DCXR antibody at 4.74ug/ml
Lane 1: MCF7 whole cell lysate