CCP110 Antibody

Artikelnummer: ASB-OACA08554
Artikelname: CCP110 Antibody
Artikelnummer: ASB-OACA08554
Hersteller Artikelnummer: OACA08554
Alternativnummer: ASB-OACA08554-100UL,ASB-OACA08554-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA)
Konjugation: Unconjugated
Alternative Synonym: centriolar coiled-coil protein 110kDa,centriolar coiled-coil protein of 110 kDa,centrosomal protein CP110,centrosomal protein of 110 kDa,Cep110,CP110.
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Klonalität: Polyclonal
NCBI: 9738
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human rectum tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Western blot
All lanes: CCP110 antibody at 4.6ug/ml
Lane 1: Hela whole cell lysate