ERLIN2 Antibody
Artikelnummer:
ASB-OACA08617
- Bilder (3)
| Artikelname: | ERLIN2 Antibody |
| Artikelnummer: | ASB-OACA08617 |
| Hersteller Artikelnummer: | OACA08617 |
| Alternativnummer: | ASB-OACA08617-100UL,ASB-OACA08617-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human Erlin-2 protein (212-339AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | C8orf2,endoplasmic reticulum lipid raft-associated protein 2,epididymis secretory sperm binding protein,erlin-2,NET32,spastic paraplegia 18 (autosomal dominant),SPFH domain family, member 2,SPFH2,SPG18,stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2. |
| Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618). |
| Klonalität: | Polyclonal |
| NCBI: | 11160 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded humanAtestis tissue at dilution 1:100 |
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Western blot All lanes: ERLIN2 antibody at 3.1 ug/ml Lane 1: 293T whole cell lysate< |
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