NUF2 Antibody

Artikelnummer: ASB-OACA08785
Artikelname: NUF2 Antibody
Artikelnummer: ASB-OACA08785
Hersteller Artikelnummer: OACA08785
Alternativnummer: ASB-OACA08785-100UL,ASB-OACA08785-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Kinetochore protein Nuf2 protein (165-464AA)
Konjugation: Unconjugated
Alternative Synonym: cancer/testis antigen 106,CDCA1,cell division cycle associated 1,cell division cycle-associated protein 1,CT106,hNuf2,hNuf2R,hsNuf2,kinetochore protein Nuf2,NDC80 kinetochore complex component NUF2,NUF2, NDC80 kinetochore complex component, homolog,NUF2R.
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
Klonalität: Polyclonal
NCBI: 83540
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human liver tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution of 1:100
Western blot
All lanes: NUF2 antibody at 5.29 ug/ml
Lane 1: Mouse live