MARK1 Antibody
Artikelnummer:
ASB-OACA08910
- Bilder (3)
| Artikelname: | MARK1 Antibody |
| Artikelnummer: | ASB-OACA08910 |
| Hersteller Artikelnummer: | OACA08910 |
| Alternativnummer: | ASB-OACA08910-100UL,ASB-OACA08910-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | Recombinant Human Serine/threonine-protein kinase MARK1 protein (560-700AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | MAP/microtubule affinity-regulating kinase 1,MARK,PAR1 homolog c,Par1c,Par-1c,serine/threonine-protein kinase MARK1. |
| Serine/threonine-protein kinase (PubMed:23666762). Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3). |
| Klonalität: | Polyclonal |
| NCBI: | 4139 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100 |
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Western blot All lanes: MARK1 antibody IgG at 2.65ug/ml+ Rat heart tissue Secondary |
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