Recombinant TIGIT (Gly21~Leu234) expressed in E.coli
Alternative Synonym:
T-cell immunoreceptor with Ig and ITIM domains,V-set and immunoglobulin domain containing 9,V-set and immunoglobulin domain-containing protein 9,V-set and transmembrane domain containing 3,V-set and transmembrane domain-containing protein 3,VSIG9,VSIG9, VSTM3,VSTM3,Washington University cell adhesion molecule,WUCAM.
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
