Recombinant protein encompassing a sequence within the center region of human Prohibitin. The exact sequence is proprietary.
Alternative Synonym:
PHB1, HEL-215, HEL-S-54e
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3 UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
