Recombinant protein encompassing a sequence within the N-terminus region of human CRM1. The exact sequence is proprietary.
Alternative Synonym:
emb, CRM1, exp1, CRM-1
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
