Recombinant protein encompassing a sequence within the center region of human GTF2A1. The exact sequence is proprietary.
Alternative Synonym:
TF2A1, TFIIA, TFIIAL, TFIIA-42
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]
