Recombinant protein encompassing a sequence within the center region of human POFUT1. The exact sequence is proprietary.
Alternative Synonym:
DDD2, FUT12, O-FUT, OFUCT1, O-Fuc-T, O-FucT-1
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.