Recombinant protein encompassing a sequence within the N-terminus region of human SNF2H. The exact sequence is proprietary.
Alternative Synonym:
ISWI, SNF2H, hISWI, hSNF2H, WCRF135
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.
