Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human WIPI2. The exact sequence is proprietary.
Alternative Synonym:
Atg21, ATG18B, CGI-50, IDDSSA, WIPI-2
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]
