Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. The exact sequence is proprietary.
Alternative Synonym:
HLF, MOP2, ECYT4, HIF2A, PASD2, bHLHe73
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.