Recombinant protein encompassing a sequence within the N-terminus region of human YAP1. The exact sequence is proprietary.
Alternative Synonym:
YAP, YKI, COB1, YAP2, YAP65
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
