ELOVL7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ELOVL7. The immunogen is located within amino acids 40 - 90 of ELOVL7.
Konjugation:
Unconjugated
Alternative Synonym:
3-keto acyl-CoA synthase ELOVL7,elongation of very long chain fatty acids protein 7,ELOVL FA elongase 7,ELOVL family member 7, elongation of long chain fatty acids,ELOVL fatty acid elongase 7,very long chain 3-ketoacyl-CoA synthase 7,very long chain 3-oxoacyl-CoA synthase 7.
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
