The antiserum was produced against synthesized peptide derived from human ERCC5. AA range:131-180
Alternative Synonym:
ERCC5, ERCM2, XPG, XPGC, DNA repair protein complementing XP-G cells, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein
This gene encodes a single-strand specific DNA endonuclease that makes the 3 incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcript