The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590
Alternative Synonym:
MSH2, DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (R
