Nucleolar protein 3 Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit
Artikelnummer:
BSS-BS-7080R-BF488
Hersteller Artikelnummer:
bs-7080R-BF488
Alternativnummer:
BSS-BS-7080R-BF488-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF
Spezies Reaktivität:
Mouse
Konjugation:
BF488
Alternative Synonym:
Apoptosis repressor with CARD, ARC, Muscle enriched cytoplasmic protein, MYC, Myp, NOP, Nop30, Nucleolar protein 3 apoptosis repressor with CARD domain, Nucleolar protein 3, Nucleolar protein of 30 kDa, NOL3_MOUSE .
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD)bcontaining molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf 1, caspase 9 and caspase 2. Apoptosis repressor with CARD is a CARD domain containing protein that interacts with caspase 2 and 8 to inhibit enzymatic activity of caspase 8. Apoptosis repressor with CARD suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR 1, and DR3. The mRNA of Apoptosis repressor with CARD is primarily expressed in skeletal muscle and cardiac tissue. The nuclear isoform (1/Nop30) may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis.
