Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE05880
Artikelname: Phospho-c-Myc (T58) (1A2) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE05880
Hersteller Artikelnummer: AMRe05880
Alternativnummer: EKL-AMRE05880-50UL, EKL-AMRE05880-100UL, EKL-AMRE05880-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: MRTL, MYC, Myc proto-oncogene protein, c-myc,
Myc a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors. Seems to activate the transcription of growth-related genes. Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5-CAC[GA]TG-3 (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).
Klonalität: Monoclonal
Molekulargewicht: 49kDa
NCBI: 4609
UniProt: P01106
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: MYC
Application Verdünnung: WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:1000