BDNF (7L10) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE07524
Artikelname: BDNF (7L10) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE07524
Hersteller Artikelnummer: AMRe07524
Alternativnummer: EKL-AMRE07524-50UL, EKL-AMRE07524-100UL, EKL-AMRE07524-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ICC, IF, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: BDNF,MGC34632,Abrineurin, ANON2, Brain Derived Neurotrophic Factor, Neurotrophin,BULN2,
Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Klonalität: Monoclonal
Molekulargewicht: 28kDa
NCBI: 627
UniProt: P23560
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: BDNF
Application Verdünnung: WB 1:1000-1:10000,IHC 1:200-1:500,ICC/IF 1:200-1:500,IF-P 1:200-1:500



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