BOB1 (10L9) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE07623
Artikelname: BOB1 (10L9) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE07623
Hersteller Artikelnummer: AMRe07623
Alternativnummer: EKL-AMRE07623-50UL, EKL-AMRE07623-100UL, EKL-AMRE07623-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: BOB 1, BOB-1, OBF 1, OBF1, OCA B, OCA-B, OCAB, OCT binding factor 1, Pou2af1,
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2 (PubMed:7859290). It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2 (PubMed:7779176). It has no intrinsic DNA-binding activity. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2 (PubMed:7779176). It is essential for the response of B-cells to antigens and required for the formation of germinal centers (PubMed:7623806, PubMed:7859290). Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator (By similarity).
Klonalität: Monoclonal
Molekulargewicht: 27kDa
NCBI: 5450
UniProt: Q16633
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: POU2AF1
Application Verdünnung: WB 1:1000-1:5000