CD19 (16P1) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE08254
Artikelname: CD19 (16P1) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE08254
Hersteller Artikelnummer: AMRe08254
Alternativnummer: EKL-AMRE08254-50UL, EKL-AMRE08254-100UL, EKL-AMRE08254-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, IHC, WB
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4,
CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores (PubMed:9382888, PubMed:9317126, PubMed:12387743, PubMed:16672701). Is not required for early steps during B cell differentiation in the blood marrow (PubMed:9317126). Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:2463100, PubMed:1373518). Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:9317126, PubMed:12387743, PubMed:16672701).
Klonalität: Monoclonal
Molekulargewicht: 61kDa
NCBI: 930
UniProt: P15391
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: CD19
Application Verdünnung: WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:1000,FC 1:500-1:1000



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