CD35 (18O19) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE08374
Artikelname: CD35 (18O19) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE08374
Hersteller Artikelnummer: AMRe08374
Alternativnummer: EKL-AMRE08374-50UL, EKL-AMRE08374-100UL, EKL-AMRE08374-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IF, IHC, WB
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: C3BR, C4BR CD35, CR1, Knops blood group antigen,
Mediates cellular binding of particles and immune complexes that have activated complement. Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069). Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation (PubMed:2963069). Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d (PubMed:2972794, PubMed:8175757). Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells (PubMed:25742728).
Klonalität: Monoclonal
Molekulargewicht: 224kDa
NCBI: 1378
UniProt: P17927
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: CR1
Application Verdünnung: WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200



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