CD40L (15O10) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE08392
Artikelname: CD40L (15O10) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE08392
Hersteller Artikelnummer: AMRe08392
Alternativnummer: EKL-AMRE08392-50UL, EKL-AMRE08392-100UL, EKL-AMRE08392-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse
Konjugation: Unconjugated
Alternative Synonym: CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, CD40LG, CD40L, TNFSF5, TRAP,
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B (PubMed:15067037, PubMed:31331973). Induces the activation of kinases MAPK8 and PAK2 in T-cells (PubMed:15067037). Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity).
Klonalität: Monoclonal
Molekulargewicht: 29kDa
NCBI: 959
UniProt: P29965
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: CD40LG
Application Verdünnung: WB 1:1000-1:5000



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