MAD1 (9O1) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE13551
Artikelname: MAD1 (9O1) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE13551
Hersteller Artikelnummer: AMRe13551
Alternativnummer: EKL-AMRE13551-50UL, EKL-AMRE13551-100UL, EKL-AMRE13551-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: hMAD1, HsMAD1, MAD1, MAD1L1, PIG9, TP53I9, TXBP181,
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate (PubMed:10049595, PubMed:20133940, PubMed:29162720). Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1 (O-MAD2) and promotes the conversion of O-MAD2 to C-MAD2, which ensures mitotic checkpoint signaling (PubMed:29162720).
Klonalität: Monoclonal
Molekulargewicht: 83kDa
NCBI: 8379
UniProt: Q9Y6D9
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: MAD1L1
Application Verdünnung: WB 1:1000-1:5000