NCX1 (13Y2) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE14460
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| Artikelname: | NCX1 (13Y2) Rabbit Monoclonal Antibody, Unconjugated |
| Artikelnummer: | EKL-AMRE14460 |
| Hersteller Artikelnummer: | AMRe14460 |
| Alternativnummer: | EKL-AMRE14460-50UL, EKL-AMRE14460-100UL, EKL-AMRE14460-200UL |
| Hersteller: | EnkiLife |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Konjugation: | Unconjugated |
| Alternative Synonym: | Na+/Ca2+ exchanger, NCX1, SLC8A1, |
| Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores. Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions. |
| Klonalität: | Monoclonal |
| Molekulargewicht: | 109kDa |
| NCBI: | 6546 |
| UniProt: | P32418 |
| Puffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle. |
| Reinheit: | Affinity purification |
| Formulierung: | Liquid |
| Target-Kategorie: | SLC8A1 |
| Application Verdünnung: | WB 1:1000-1:5000 |
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