PGDH (9T2) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE16028
Artikelname: PGDH (9T2) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE16028
Hersteller Artikelnummer: AMRe16028
Alternativnummer: EKL-AMRE16028-50UL, EKL-AMRE16028-100UL, EKL-AMRE16028-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, IHC, WB
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: 15-PGDH, Hpgd, PGDH, PGDH1, PHOAR1, SDR36C1,
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. Primary enzyme catalyzing the conversion of hydroxylated arachidonic acid species to their corresponding oxidized metabolites (Probable). Prostaglandin inactivation, catalyzes the first step in the catabolic pathway of the prostaglandins. Contributes to the regulation of events that are under the control of prostaglandin levels (PubMed:15574495, PubMed:16828555, PubMed:8086429). Catalyzes the NAD- dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (PubMed:10837478). Converts 11(R)-HETE to 11-oxo-5,8,12,14-(Z,Z,E,Z)- eicosatetraenoic acid (ETE) (PubMed:21916491). Has hydroxylated docosahexaenoic acid metabolites as substrates (PubMed:25586183). Converts resolvins E1, D1 and D2 to their oxo products which represents a mode of resolvins inactivation and stabilizes their anti-inflammatory actions (PubMed:16757471, PubMed:22844113).
Klonalität: Monoclonal
Molekulargewicht: 29kDa
NCBI: 3248
UniProt: P15428
Puffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: HPGD
Application Verdünnung: WB 1:1000-1:5000,IHC 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:100