TLR9 (4E13) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE18992
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| Artikelname: | TLR9 (4E13) Rabbit Monoclonal Antibody, Unconjugated |
| Artikelnummer: | EKL-AMRE18992 |
| Hersteller Artikelnummer: | AMRe18992 |
| Alternativnummer: | EKL-AMRE18992-50UL, EKL-AMRE18992-100UL, EKL-AMRE18992-200UL |
| Hersteller: | EnkiLife |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | IP, WB |
| Spezies Reaktivität: | Human |
| Konjugation: | Unconjugated |
| Alternative Synonym: | CD289, TLR9, Toll like receptor 9, Toll like receptor 9 isoform A precursor, Toll like receptor 9 isoform B, |
| Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:11564765, PubMed:17932028). Controls lymphocyte response to Helicobacter infection (By similarity). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed:23857366). |
| Klonalität: | Monoclonal |
| Molekulargewicht: | 116kDa |
| NCBI: | 54106 |
| UniProt: | Q9NR96 |
| Puffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle. |
| Reinheit: | Affinity purification |
| Formulierung: | Liquid |
| Target-Kategorie: | TLR9 |
| Application Verdünnung: | WB 1:500-1:2000,IP 1:20-1:50 |
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