TP53BP2,ASPP2,BBP,Apoptosis-stimmuLating of p53 protein 2 ,Bcl2-binding protein,Bbp,Renal carcinoma antigen NY-REN-51,Tumor suppressor p53-binding protein 2,53BP2,p53-binding protein 2,p53BP2,
Cell localization:Cytoplasm, perinuclear region. Nucleus. Note=Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42..This gene encodes a member of the ASPP (apoptosis-stimµLating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regµLates apoptosis and cell growth through interactions with other regµLatory molecµLes including members of the p53 family. MµLtiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, JµL 2008],
