Cell localization:Cytoplasm, Nucleus.This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regµLation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene coµLd be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, JµL 2008],
