BAK1,BAK,BCL2L7,CDN1,Bcl-2 homologous antagonist/killer,Apoptosis regmuLator BAK,Bcl-2-like protein 7,Bcl2-L-7
Cell localization:Mitochondrion outer membrane.The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regµLators that are involved in a wide variety of cellµLar activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, JµL 2008],
